Khlong Phasi Charoen (Thai: คลองภาษีเจริญ) is a canal in western part of central Thailand. The canal links the Tha Chin river to Khlong Bangkok Yai. It starts at Khlong Bangkok Yai nearby Wat Paknam Phasi Charoen, Bangkok and ends southward of Wat Ang Thong, Tambon Don Kai Di, Krathum Baen district, Samut Sakhon Province. It is approximately 30 km long.
The canal project was initiated by Phra Phasi Sombat Boriboon (พระภาษีสมบัติบริบูรณ์), who later became Phraya Phison Sombat Boriboon (พระยาพิสณฑ์สมบัติบริบูรณ์). Originally Phasi Charoen proposed to fund the project in exchange for the right to collect toll for the passage. It was approved by King Mongkut (Rama IV), however, with the fund given via tax deduction from the amount Phra Phasi Sombat Boriboon had to collect, thus making the canal toll-free. The construction began in 1866 and completed in 1872 and the canal was named after the man who had overseen the project.